The aim of this project is to create a perfusable cardiac patch, intended for repairing damaged areas of the cardiac muscle. The patch is created using 3D bioprinting technology, which allows for the controlled and automatic deposition of biological and structural materials that will form the construct. Endothelial cells are deposited within an extracellular matrix mimicking material, enabling them to spontaneously organize into vascular networks. Cardiomyocytes are obtained by differentiating induced pluripotent stem cells (iPSCs) and seeded along the endothelial cells, creating a more complex tissue.
